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we're going to take a moment now to go

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down to the marshall space flight center

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in huntsville alabama where laurie megs

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is standing by lori let's talk about the

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new study that's on space station that's

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looking at cardiovascular health on the

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astronauts it's called cardio ox for

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short and it's looking at the space

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related space-related cardiovascular

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disease risk to long-duration astronauts

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steve platts is the principal

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investigator at the johnson space center

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and he tells us more about this study

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the short title is

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cardio ox and that stands for

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cardiovascular oxidative stress

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and we're looking at how space flight

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may induce

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oxidative stress and inflammation in

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astronauts it's actually something you

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hear about all the time so when you see

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these

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medications or vitamins but vitamin e

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vitamin c they say they're antioxidants

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and you take an antioxidant to fight

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oxidative stress so it's a natural

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process in the body every time you burn

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atp for your cells to do anything you

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produce these

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free radicals and your body also

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produces things that fight them and you

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get this balance between the two and

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that's when everything is okay when you

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get into stressful situations or or have

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other issues that get out of balance and

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that's when it can become a problem

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so they're out of balance what we see in

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in astronauts or have we even our

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hypothesis is that we're out of balance

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there's a little bit of data that shows

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we could be out of balance in space

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flight but on earth we know that a lot

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of the situations that they end up in in

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space

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the deconditioning the the diet they

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have the radiation exposure all those

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things cause oxidative stress here on

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earth so our hypothesis is that it's

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doing the same thing in space flight so

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how are we going to prove this is true

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well we have 12 12 astronauts that we're

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going to study and we're taking blood

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samples and urine samples and at the

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same time we're looking at how the blood

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vessels respond so we're getting a

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measure of structure and function and we

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can compare the biomarkers that we're

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getting that show us what degree of

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inflammation and oxidative stress we

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have and what the functional consequence

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of that is

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what do we hope to gain from this

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it'll it'll be helpful for the crew but

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it's also potentially helpful here on

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earth so

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there are all these different hypotheses

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about oxidative stress and inflammation

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and how they can lead to coronary artery

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disease and that's one of our major

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research gaps

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here at nasa is

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do does space flight induce any kind of

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cardiovascular issues long-term not just

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while the crew are in flight but when

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they return are we putting them at

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additional risk for

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for a heart attack or something else and

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this study will help us

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to see if we have any potential

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pre-clinical issues and

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in the time frames that we're talking

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about we wouldn't be able to see

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full-blown

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clinical issues but the the measures

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that we're using can predict future

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potential for atherosclerosis

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three astronauts are actively

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participating in pre-flight and training

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activities for this experiment one

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astronaut has actually completed some

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in-flight data collection and three more

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have just signed on to participate in

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the study we'll see the first

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post-flight data collection sessions

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sometime next spring now let's take a

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live look into the payload operations

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integration center and josh as you

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mentioned they are participating in that

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simulation i actually walked in to find

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out what was going on this morning and

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they told me now's not a good time so i

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just turned around and left you know

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they have to be prepared they say

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sometimes they have to train together

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for a bad day that they hope never

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happens and

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today is that day but it's just training

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and it's well worth it to be prepared

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and you can also see they're waiting for

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santa claus too those hats and

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and stockings so hopefully somebody will

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put something in there that'll do it for

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us at the payload operations integration